Tag: hypertension

• MRFIT Study – What did it tell us?

  The Australian Broadcaster ABC televised the program Heart of the Matter Part 1 - Dietary Villains on Thursday, 24 October 2013. This program listed the MRFIT study as more evidence that cholesterol is not implicated in heart disease.

  The Multiple Risk Factor Intervention Trial (MRFIT) was a coronary heart disease prevention trial that was conducted at 22 US clinical centres (18 cities) from 1973 to 1982. The multiple risks evaluated were elevated serum cholesterol, elevated blood pressure and cigarette smoking.

  A number of popular commentators use this trial as proof that cholesterol is not implicated in heart disease.

  The tobacco industry also used the results of the MRFIT study to argue that smoking is not harmful.

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  30 April 2014

• Men’s Shed Morpeth – 28 February 2014

  The transcript of a talk given at Morpeth Men's Shed on 28 February 2014.

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  27 February 2014

• What is a Heart Attack?

  Below is an overview of the mechanism that leads to cardiac myocardial infarctions (or heart attack). It took many decades for a basic understanding of this process.

  The consensus at the beginning of the 20th century was that heart disease is a normal part of aging. In 1913, a 28 year old pathologist, Nikolay Anitschkow (or Anichkov), working at the Military Medical Academy in St. Petersburg, showed that by feeding rabbits cholesterol dissolved in sunflower oil induced vascular lesions closely resembling those of human atherosclerosis, both grossly and microscopically. Controls fed only the sunflower oil showed no lesions.

  Another difficulty in understanding heart disease is that there are a number of factors involved. Researchers, practitioners and the public become attached to one aspect. Some argue passionately regarding one aspect of heart disease and become blind to other factors.

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  6 January 2014